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DZNep promotes mouse bone defect healing via enhancing both osteogenesis and osteoclastogenesis

BACKGROUND: Enhancer of zeste homolog 2 (EZH2) is a novel oncogene that can specifically trimethylate the histone H3 lysine 27 (H3K27me3) to transcriptionally inhibit the expression of downstream tumor-suppressing genes. As a small molecular inhibitor of EZH2, 3-Deazaneplanocin (DZNep) has been wide...

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Detalles Bibliográficos
Autores principales:	Cao, Xiankun, He, Wenxin, Rong, Kewei, Xu, Shenggui, Chen, Zhiqian, Liang, Yuwei, Han, Shuai, Zhou, Yifan, Yang, Xiao, Ma, Hui, Qin, An, Zhao, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686256/ https://www.ncbi.nlm.nih.gov/pubmed/34930462 http://dx.doi.org/10.1186/s13287-021-02670-6

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