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Targeting Ionotropic Glutamate Receptors in the Treatment of Epilepsy
BACKGROUND: A dysfunction in glutamate neurotransmission is critical for seizure. Glutamate is the major excitatory drive in the cerebral cortex, where seizures occur. Glutamate acts via (i) ionotropic (iGlu) receptors, which are ligand-gated ion channels mediating fast excitatory synaptic transmiss...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686308/ https://www.ncbi.nlm.nih.gov/pubmed/32867642 http://dx.doi.org/10.2174/1570159X18666200831154658 |