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ESR1 PvuII polymorphism: from risk factor to prognostic and predictive factor of the success of primary systemic therapy in advanced breast cancer

BACKGROUND: The ESR1 gene encodes Estrogen Receptor alpha (ERα), which plays a role in the tumourigenesis of breast cancer. A single nucleotide polymorphism (SNP) in intron 1 of this gene called ESR1 PvuII (rs2234693) has been reported to increase the risk of breast cancer. This study aimed to inves...

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Detalles Bibliográficos
Autores principales: Karsono, Ramadhan, Haryono, Samuel J., Karsono, Bambang, Harahap, Wirsma Arif, Pratiwi, Yulia, Aryandono, Teguh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686387/
https://www.ncbi.nlm.nih.gov/pubmed/34930150
http://dx.doi.org/10.1186/s12885-021-09083-x

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