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Cancer-associated fibroblasts promote oral squamous cell carcinoma progression through LOX-mediated matrix stiffness

BACKGROUND: Cancer-associated fibroblasts (CAFs), the most abundant cells in the tumor microenvironment, have prominent roles in the development of solid tumors as stromal targets. However, the underlying mechanism of CAFs’ function in oral squamous cell carcinoma (OSCC) development remains unclear....

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Yi, Zhu, Wei-Wen, Wang, Meng-Yao, Zhai, Run-Dong, Wang, Qiong, Shen, Wei-Li, Liu, Lai-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686394/
https://www.ncbi.nlm.nih.gov/pubmed/34930321
http://dx.doi.org/10.1186/s12967-021-03181-x