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Cancer-associated fibroblasts promote oral squamous cell carcinoma progression through LOX-mediated matrix stiffness
BACKGROUND: Cancer-associated fibroblasts (CAFs), the most abundant cells in the tumor microenvironment, have prominent roles in the development of solid tumors as stromal targets. However, the underlying mechanism of CAFs’ function in oral squamous cell carcinoma (OSCC) development remains unclear....
Autores principales: | Zhang, Jia-Yi, Zhu, Wei-Wen, Wang, Meng-Yao, Zhai, Run-Dong, Wang, Qiong, Shen, Wei-Li, Liu, Lai-Kui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686394/ https://www.ncbi.nlm.nih.gov/pubmed/34930321 http://dx.doi.org/10.1186/s12967-021-03181-x |
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