Comparison of Three Complementary Analytical Techniques for the Evaluation of the Biosimilar Comparability of a Monoclonal Antibody and an Fc-Fusion Protein

In this work, a monoclonal antibody, adalimumab, and an Fc-fusion protein, etanercept, were studied and compared to one of their biosimilars. Samples submitted to stress conditions (agitation and high temperature) were used for method development. The developed methods were also applied to samples r...

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Detalles Bibliográficos
Autores principales: Demelenne, Alice, Ben Yahia, Arij, Lempereur, Delphine, Crommen, Jacques, Servais, Anne-Catherine, Fradi, Ines, Fillet, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686473/
https://www.ncbi.nlm.nih.gov/pubmed/34938718
http://dx.doi.org/10.3389/fchem.2021.782099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686473/
https://www.ncbi.nlm.nih.gov/pubmed/34938718
http://dx.doi.org/10.3389/fchem.2021.782099

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