TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD

BACKGROUND: Duchenne muscular dystrophy (DMD) is an X-linked inherited disease caused by mutations in the gene encoding dystrophin that leads to a severe and ultimately life limiting muscle-wasting condition. Recombinant adeno-associated vector (rAAV)-based gene therapy is promising, but the size of...

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Detalles Bibliográficos
Autores principales: Creisméas, Anna, Gazaille, Claire, Bourdon, Audrey, Lallemand, Marc-Antoine, François, Virginie, Allais, Marine, Ledevin, Mireille, Larcher, Thibaut, Toumaniantz, Gilles, Lafoux, Aude, Huchet, Corinne, Anegon, Ignacio, Adjali, Oumeya, Le Guiner, Caroline, Fraysse, Bodvaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686557/
https://www.ncbi.nlm.nih.gov/pubmed/34930315
http://dx.doi.org/10.1186/s12967-021-03191-9

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