Hidden biases in germline structural variant detection

BACKGROUND: Genomic structural variations (SV) are important determinants of genotypic and phenotypic changes in many organisms. However, the detection of SV from next-generation sequencing data remains challenging. RESULTS: In this study, DNA from a Chinese family quartet is sequenced at three diff...

Descripción completa

Detalles Bibliográficos
Autores principales: Khayat, Michael M., Sahraeian, Sayed Mohammad Ebrahim, Zarate, Samantha, Carroll, Andrew, Hong, Huixiao, Pan, Bohu, Shi, Leming, Gibbs, Richard A., Mohiyuddin, Marghoob, Zheng, Yuanting, Sedlazeck, Fritz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686633/
https://www.ncbi.nlm.nih.gov/pubmed/34930391
http://dx.doi.org/10.1186/s13059-021-02558-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686633/
https://www.ncbi.nlm.nih.gov/pubmed/34930391
http://dx.doi.org/10.1186/s13059-021-02558-x

Ejemplares similares