NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance

SilE and SilB are both proteins involved in the silver efflux pump found in Gram-negative bacteria such as S. typhimurium. Using model peptides along with NMR and CD experiments, we show how SilE may store silver ions prior to delivery and we hypothesize for the first time the interplay between SilB...

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Detalles Bibliográficos
Autores principales: Babel, Lucille, Nguyen, Minh-Ha, Mittelheisser, Cédric, Martin, Marie, Fromm, Katharina M., Walker, Olivier, Hologne, Maggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686694/
https://www.ncbi.nlm.nih.gov/pubmed/34396382
http://dx.doi.org/10.1039/d1cc02597j
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author Babel, Lucille
Nguyen, Minh-Ha
Mittelheisser, Cédric
Martin, Marie
Fromm, Katharina M.
Walker, Olivier
Hologne, Maggy
author_facet Babel, Lucille
Nguyen, Minh-Ha
Mittelheisser, Cédric
Martin, Marie
Fromm, Katharina M.
Walker, Olivier
Hologne, Maggy
author_sort Babel, Lucille
collection PubMed
description SilE and SilB are both proteins involved in the silver efflux pump found in Gram-negative bacteria such as S. typhimurium. Using model peptides along with NMR and CD experiments, we show how SilE may store silver ions prior to delivery and we hypothesize for the first time the interplay between SilB and SilE.
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spelling pubmed-86866942022-01-11 NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance Babel, Lucille Nguyen, Minh-Ha Mittelheisser, Cédric Martin, Marie Fromm, Katharina M. Walker, Olivier Hologne, Maggy Chem Commun (Camb) Chemistry SilE and SilB are both proteins involved in the silver efflux pump found in Gram-negative bacteria such as S. typhimurium. Using model peptides along with NMR and CD experiments, we show how SilE may store silver ions prior to delivery and we hypothesize for the first time the interplay between SilB and SilE. The Royal Society of Chemistry 2021-08-09 /pmc/articles/PMC8686694/ /pubmed/34396382 http://dx.doi.org/10.1039/d1cc02597j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Babel, Lucille
Nguyen, Minh-Ha
Mittelheisser, Cédric
Martin, Marie
Fromm, Katharina M.
Walker, Olivier
Hologne, Maggy
NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance
title NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance
title_full NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance
title_fullStr NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance
title_full_unstemmed NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance
title_short NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance
title_sort nmr reveals the interplay between sile and silb model peptides in the context of silver resistance
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686694/
https://www.ncbi.nlm.nih.gov/pubmed/34396382
http://dx.doi.org/10.1039/d1cc02597j
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