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Liver-Specific Nonviral Gene Delivery of Fibroblast Growth Factor 21 Protein Expression in Mice Regulates Body Mass and White/Brown Fat Respiration

Viral-mediated in vivo gene delivery methods currently dominate among therapeutic strategies within the clinical and experimental settings, albeit with well documented limitations arising from immunologic constraints. In this study, we demonstrate the utility of nonviral hepatotropic in vivo gene de...

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Detalles Bibliográficos
Autores principales:	Girer, Nathaniel G., Rontoyanni, Victoria G., Joshi, Aditya, Patrikeev, Igor, Murton, Andrew J., Porter, Craig, Motamedi, Massoud, Elferink, Cornelis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Endocrine and Diabetes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686718/ https://www.ncbi.nlm.nih.gov/pubmed/34074713 http://dx.doi.org/10.1124/jpet.121.000514

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