(18)FDG PET-CT in sporadic Creutzfeldt-Jakob disease, correlated with MRI and histology

We present a case of sporadic Creutzfeldt–Jakob disease with profoundly abnormal 18fluoro-deoxy-glucose positron emission tomography with computed tomography (FDG PET-CT) at an early stage, and correlate this with the clear findings at magnetic resonance imaging and also postmortem histology. Prion...

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Detalles Bibliográficos
Autores principales: Morley, Nicholas C. D., Hofer, Monika, Wilkinson, Philip, Bradley, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686746/
https://www.ncbi.nlm.nih.gov/pubmed/35018165
http://dx.doi.org/10.4103/wjnm.wjnm_5_21
Descripción
Sumario:We present a case of sporadic Creutzfeldt–Jakob disease with profoundly abnormal 18fluoro-deoxy-glucose positron emission tomography with computed tomography (FDG PET-CT) at an early stage, and correlate this with the clear findings at magnetic resonance imaging and also postmortem histology. Prion diseases are rare but important causes of cognitive impairment. The role of FDG PET-CT is discussed, along with other investigations such as electroencephalography and cerebro-spinal fluid analyses.

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