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Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686747/ https://www.ncbi.nlm.nih.gov/pubmed/35018155 http://dx.doi.org/10.4103/wjnm.wjnm_74_21 |
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author | Purkayastha, Abhishek Suhag, Virender Taneja, Sachin Husain, Azhar |
author_facet | Purkayastha, Abhishek Suhag, Virender Taneja, Sachin Husain, Azhar |
author_sort | Purkayastha, Abhishek |
collection | PubMed |
description | Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly aggressive squamous cell PC in a 46-year-old male with fulminant upfront distant dissemination to left supraclavicular lymph nodes (LNs) without involving the inguinal and pelvic nodes detected by whole-body (18)F-fluorodeoxyglucose positron-emission tomography scan. The scan also detected lytic destructive lesion involving the pelvic and adjacent bones with infiltration of skeletal muscles. He was treated with palliative radiotherapy to the wight-bearing sites followed by systemic chemotherapy. A thorough review of literature reveals that our case may be one of the rarest cases ever reported in world literature where an asymptomatic PC presents with upfront supraclavicular LN metastasis bypassing the inguinal, pelvic, and retroperitoneal LN chains. |
format | Online Article Text |
id | pubmed-8686747 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-86867472022-01-10 Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case Purkayastha, Abhishek Suhag, Virender Taneja, Sachin Husain, Azhar World J Nucl Med Case Report Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly aggressive squamous cell PC in a 46-year-old male with fulminant upfront distant dissemination to left supraclavicular lymph nodes (LNs) without involving the inguinal and pelvic nodes detected by whole-body (18)F-fluorodeoxyglucose positron-emission tomography scan. The scan also detected lytic destructive lesion involving the pelvic and adjacent bones with infiltration of skeletal muscles. He was treated with palliative radiotherapy to the wight-bearing sites followed by systemic chemotherapy. A thorough review of literature reveals that our case may be one of the rarest cases ever reported in world literature where an asymptomatic PC presents with upfront supraclavicular LN metastasis bypassing the inguinal, pelvic, and retroperitoneal LN chains. Wolters Kluwer - Medknow 2021-11-01 /pmc/articles/PMC8686747/ /pubmed/35018155 http://dx.doi.org/10.4103/wjnm.wjnm_74_21 Text en Copyright: © 2021 World Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Purkayastha, Abhishek Suhag, Virender Taneja, Sachin Husain, Azhar Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case |
title | Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case |
title_full | Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case |
title_fullStr | Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case |
title_full_unstemmed | Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case |
title_short | Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case |
title_sort | carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)f-fluorodeoxyglucose positron emission tomography scan: report of an extremely rare and aggressive case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686747/ https://www.ncbi.nlm.nih.gov/pubmed/35018155 http://dx.doi.org/10.4103/wjnm.wjnm_74_21 |
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