Cargando…

Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case

Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Purkayastha, Abhishek, Suhag, Virender, Taneja, Sachin, Husain, Azhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686747/
https://www.ncbi.nlm.nih.gov/pubmed/35018155
http://dx.doi.org/10.4103/wjnm.wjnm_74_21
_version_ 1784618070261628928
author Purkayastha, Abhishek
Suhag, Virender
Taneja, Sachin
Husain, Azhar
author_facet Purkayastha, Abhishek
Suhag, Virender
Taneja, Sachin
Husain, Azhar
author_sort Purkayastha, Abhishek
collection PubMed
description Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly aggressive squamous cell PC in a 46-year-old male with fulminant upfront distant dissemination to left supraclavicular lymph nodes (LNs) without involving the inguinal and pelvic nodes detected by whole-body (18)F-fluorodeoxyglucose positron-emission tomography scan. The scan also detected lytic destructive lesion involving the pelvic and adjacent bones with infiltration of skeletal muscles. He was treated with palliative radiotherapy to the wight-bearing sites followed by systemic chemotherapy. A thorough review of literature reveals that our case may be one of the rarest cases ever reported in world literature where an asymptomatic PC presents with upfront supraclavicular LN metastasis bypassing the inguinal, pelvic, and retroperitoneal LN chains.
format Online
Article
Text
id pubmed-8686747
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-86867472022-01-10 Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case Purkayastha, Abhishek Suhag, Virender Taneja, Sachin Husain, Azhar World J Nucl Med Case Report Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly aggressive squamous cell PC in a 46-year-old male with fulminant upfront distant dissemination to left supraclavicular lymph nodes (LNs) without involving the inguinal and pelvic nodes detected by whole-body (18)F-fluorodeoxyglucose positron-emission tomography scan. The scan also detected lytic destructive lesion involving the pelvic and adjacent bones with infiltration of skeletal muscles. He was treated with palliative radiotherapy to the wight-bearing sites followed by systemic chemotherapy. A thorough review of literature reveals that our case may be one of the rarest cases ever reported in world literature where an asymptomatic PC presents with upfront supraclavicular LN metastasis bypassing the inguinal, pelvic, and retroperitoneal LN chains. Wolters Kluwer - Medknow 2021-11-01 /pmc/articles/PMC8686747/ /pubmed/35018155 http://dx.doi.org/10.4103/wjnm.wjnm_74_21 Text en Copyright: © 2021 World Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Purkayastha, Abhishek
Suhag, Virender
Taneja, Sachin
Husain, Azhar
Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
title Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
title_full Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
title_fullStr Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
title_full_unstemmed Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
title_short Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
title_sort carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by (18)f-fluorodeoxyglucose positron emission tomography scan: report of an extremely rare and aggressive case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686747/
https://www.ncbi.nlm.nih.gov/pubmed/35018155
http://dx.doi.org/10.4103/wjnm.wjnm_74_21
work_keys_str_mv AT purkayasthaabhishek carcinomapenismanifestingasupfrontsupraclavicularlymphnodemetastasesdetectedby18ffluorodeoxyglucosepositronemissiontomographyscanreportofanextremelyrareandaggressivecase
AT suhagvirender carcinomapenismanifestingasupfrontsupraclavicularlymphnodemetastasesdetectedby18ffluorodeoxyglucosepositronemissiontomographyscanreportofanextremelyrareandaggressivecase
AT tanejasachin carcinomapenismanifestingasupfrontsupraclavicularlymphnodemetastasesdetectedby18ffluorodeoxyglucosepositronemissiontomographyscanreportofanextremelyrareandaggressivecase
AT husainazhar carcinomapenismanifestingasupfrontsupraclavicularlymphnodemetastasesdetectedby18ffluorodeoxyglucosepositronemissiontomographyscanreportofanextremelyrareandaggressivecase