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A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT

A 67-year-old male presented to the hospital for lower back pain and left lower extremity radiculopathy. Although the patient was afebrile and white blood cell count was normal, MRI was concerning for discitis/osteomyelitis at L4-L5. Subsequently, the patient developed a right knee joint effusion an...

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Autores principales: Seifert, Kimberly D., Zohrabian, Vahe M., Ikuta, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686775/
https://www.ncbi.nlm.nih.gov/pubmed/34970097
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author Seifert, Kimberly D.
Zohrabian, Vahe M.
Ikuta, Ichiro
author_facet Seifert, Kimberly D.
Zohrabian, Vahe M.
Ikuta, Ichiro
author_sort Seifert, Kimberly D.
collection PubMed
description A 67-year-old male presented to the hospital for lower back pain and left lower extremity radiculopathy. Although the patient was afebrile and white blood cell count was normal, MRI was concerning for discitis/osteomyelitis at L4-L5. Subsequently, the patient developed a right knee joint effusion and underwent an arthrocentesis that was notable for the presence of urate crystals. A systemic urate crystal arthropathy was proposed as a potential etiology for the patient’s back pain and radiculopathy. Dual energy CT of the lumbar spine was performed, a technique which determines material composition by comparing the photon attenuation of the substance from two different x-ray energy levels. Results revealed the presence of monosodium urate crystals in the intervertebral discs. This technique is proposed as a noninvasive way to evaluate for gout in atypical locations or those difficult to sample and may replace an invasive intervertebral disc/endplate aspiration and/or biopsy. Dual energy CT should be considered in patients with elevated serum uric acid and concern for spinal involvement of gout.
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spelling pubmed-86867752021-12-29 A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT Seifert, Kimberly D. Zohrabian, Vahe M. Ikuta, Ichiro Yale J Biol Med Case Report A 67-year-old male presented to the hospital for lower back pain and left lower extremity radiculopathy. Although the patient was afebrile and white blood cell count was normal, MRI was concerning for discitis/osteomyelitis at L4-L5. Subsequently, the patient developed a right knee joint effusion and underwent an arthrocentesis that was notable for the presence of urate crystals. A systemic urate crystal arthropathy was proposed as a potential etiology for the patient’s back pain and radiculopathy. Dual energy CT of the lumbar spine was performed, a technique which determines material composition by comparing the photon attenuation of the substance from two different x-ray energy levels. Results revealed the presence of monosodium urate crystals in the intervertebral discs. This technique is proposed as a noninvasive way to evaluate for gout in atypical locations or those difficult to sample and may replace an invasive intervertebral disc/endplate aspiration and/or biopsy. Dual energy CT should be considered in patients with elevated serum uric acid and concern for spinal involvement of gout. YJBM 2021-12-29 /pmc/articles/PMC8686775/ /pubmed/34970097 Text en Copyright ©2021, Yale Journal of Biology and Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons CC BY-NC license, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes.
spellingShingle Case Report
Seifert, Kimberly D.
Zohrabian, Vahe M.
Ikuta, Ichiro
A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT
title A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT
title_full A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT
title_fullStr A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT
title_full_unstemmed A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT
title_short A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT
title_sort case of spinal infectious osteomyelitis versus gout: advanced imaging with dual energy ct
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686775/
https://www.ncbi.nlm.nih.gov/pubmed/34970097
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