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Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population

BACKGROUND: Squamous cell carcinoma (SCC) describes the carcinomatous growth in the oral cavity. Recently, various authors have described increased SCC incidence in the young population. The distribution of SCC shows varied geographic spread, with the highest distribution in Asian countries. AIMS: T...

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Autores principales: Dhumale, Annasaheb J., Mohite, Sachin, Rela, Rathi, khan, Shahla, Barbi, Wagisha, Irfan, Ahamed KA, Rangari, Priyadarshini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686900/
https://www.ncbi.nlm.nih.gov/pubmed/35017999
http://dx.doi.org/10.4103/jpbs.jpbs_228_21
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author Dhumale, Annasaheb J.
Mohite, Sachin
Rela, Rathi
khan, Shahla
Barbi, Wagisha
Irfan, Ahamed KA
Rangari, Priyadarshini
author_facet Dhumale, Annasaheb J.
Mohite, Sachin
Rela, Rathi
khan, Shahla
Barbi, Wagisha
Irfan, Ahamed KA
Rangari, Priyadarshini
author_sort Dhumale, Annasaheb J.
collection PubMed
description BACKGROUND: Squamous cell carcinoma (SCC) describes the carcinomatous growth in the oral cavity. Recently, various authors have described increased SCC incidence in the young population. The distribution of SCC shows varied geographic spread, with the highest distribution in Asian countries. AIMS: The present trial was carried out to assess the associated factors that could lead to increased risk of developing oral cancer. MATERIALS AND METHODS: Oral examination was carried out for 21 participants by a dentist and any significant oral lesion or deleterious habit if present, was recorded. The data collected were analyzed. RESULTS: Areca nut was chewed by 47.61% participants (n = 10), smoking tobacco by 76.19% (n = 16), chewing tobacco by 38.09% (n = 8), and consuming alcohol in 9 participants (42.85%). No significant difference was seen concerning age for any factor except alcohol which showed higher intake in the older group where six participants depicted alcohol intake as compared to three participants in the younger group. In participants who chewed areca nuts, 6 participants also smoked tobacco and 1 consumed alcohol. For tobacco chewing, 5 consumed alcohol and 6 also took tobacco as smoke. CONCLUSION: The present study showed that areca nut and tobacco chewing along with alcohol consumption and tobacco smoking increase the risk of developing SCC in the Indian population.
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spelling pubmed-86869002022-01-10 Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population Dhumale, Annasaheb J. Mohite, Sachin Rela, Rathi khan, Shahla Barbi, Wagisha Irfan, Ahamed KA Rangari, Priyadarshini J Pharm Bioallied Sci Original Article BACKGROUND: Squamous cell carcinoma (SCC) describes the carcinomatous growth in the oral cavity. Recently, various authors have described increased SCC incidence in the young population. The distribution of SCC shows varied geographic spread, with the highest distribution in Asian countries. AIMS: The present trial was carried out to assess the associated factors that could lead to increased risk of developing oral cancer. MATERIALS AND METHODS: Oral examination was carried out for 21 participants by a dentist and any significant oral lesion or deleterious habit if present, was recorded. The data collected were analyzed. RESULTS: Areca nut was chewed by 47.61% participants (n = 10), smoking tobacco by 76.19% (n = 16), chewing tobacco by 38.09% (n = 8), and consuming alcohol in 9 participants (42.85%). No significant difference was seen concerning age for any factor except alcohol which showed higher intake in the older group where six participants depicted alcohol intake as compared to three participants in the younger group. In participants who chewed areca nuts, 6 participants also smoked tobacco and 1 consumed alcohol. For tobacco chewing, 5 consumed alcohol and 6 also took tobacco as smoke. CONCLUSION: The present study showed that areca nut and tobacco chewing along with alcohol consumption and tobacco smoking increase the risk of developing SCC in the Indian population. Wolters Kluwer - Medknow 2021-11 2021-11-10 /pmc/articles/PMC8686900/ /pubmed/35017999 http://dx.doi.org/10.4103/jpbs.jpbs_228_21 Text en Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Dhumale, Annasaheb J.
Mohite, Sachin
Rela, Rathi
khan, Shahla
Barbi, Wagisha
Irfan, Ahamed KA
Rangari, Priyadarshini
Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population
title Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population
title_full Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population
title_fullStr Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population
title_full_unstemmed Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population
title_short Analysis of Risk Factors Associated with Squamous Cell Carcinoma in the Indian Population
title_sort analysis of risk factors associated with squamous cell carcinoma in the indian population
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686900/
https://www.ncbi.nlm.nih.gov/pubmed/35017999
http://dx.doi.org/10.4103/jpbs.jpbs_228_21
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