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Neuroscience of Peripheral Nerve Regeneration

Peripheral nerve injury involves complex molecular, cellular, and genetic events that help in ultimate regeneration of nerve. Some key factors are upregulated and some downregulated in the process of regeneration of nerve to attain almost perfect architecture. This review renders short overview abou...

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Detalles Bibliográficos
Autores principales: Paramel Mohan, Sunil, Ramalingam, Murugan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686930/
https://www.ncbi.nlm.nih.gov/pubmed/35017897
http://dx.doi.org/10.4103/jpbs.jpbs_182_21
Descripción
Sumario:Peripheral nerve injury involves complex molecular, cellular, and genetic events that help in ultimate regeneration of nerve. Some key factors are upregulated and some downregulated in the process of regeneration of nerve to attain almost perfect architecture. This review renders short overview about how the injured neurons and supporting cells like Schwann cells help in creating ample microenvironment for regeneration of peripheral nerve and their maturation.