Leptin Levels in Gingival Crevicular Fluid during Orthodontic Tooth Movement

AIM: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. MATERIALS AND METHODS: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment,...

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Detalles Bibliográficos
Autores principales: Alaguselvaraj, Joseph, Selvaraj, Kandanraj, Bhaskaran, Porselvi, Chidambaram, Sainath Muthiah, Rajasekaran, Thanigainathan, Mani, Muralimani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686992/
https://www.ncbi.nlm.nih.gov/pubmed/35017951
http://dx.doi.org/10.4103/jpbs.jpbs_285_21
Descripción
Sumario:AIM: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. MATERIALS AND METHODS: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E). RESULTS: GCF Leptin concentration in pretreatment, 6 h control and 21(st) day control were all similar. GCF leptin concentration at 6 h test tooth site was increased which was statistically significant. GCF leptin concentration in 21(st) day test tooth was decreased only a little than the control tooth which shows statistically no difference. CONCLUSION: Leptin is one of the mediators of orthodontic tooth movement.

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