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A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study

BACKGROUND: Healing unbinds a well choreographed array of cellular, physiologic, biochemical, and molecular processes directed toward restoring the integrity and functional capacity of the damaged structures. The rate and degree of healing vary among individuals but is greatest during the first few...

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Autores principales: Saha, Alangkar, Sathish, R., Setty, Suhas, Maji, Abhijit, Saha, Jayanta, Chatterjee, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686996/
https://www.ncbi.nlm.nih.gov/pubmed/35017963
http://dx.doi.org/10.4103/jpbs.jpbs_409_21
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author Saha, Alangkar
Sathish, R.
Setty, Suhas
Maji, Abhijit
Saha, Jayanta
Chatterjee, Abhishek
author_facet Saha, Alangkar
Sathish, R.
Setty, Suhas
Maji, Abhijit
Saha, Jayanta
Chatterjee, Abhishek
author_sort Saha, Alangkar
collection PubMed
description BACKGROUND: Healing unbinds a well choreographed array of cellular, physiologic, biochemical, and molecular processes directed toward restoring the integrity and functional capacity of the damaged structures. The rate and degree of healing vary among individuals but is greatest during the first few months or years after tooth loss. Evidence suggests that alveolar bone ridge resorption may be prevented, initially by reconstructive surgical techniques using several materials which are employed at the time of extraction. This droves to the development of bone substitutes materials such as hydroxyapatite, beta tricalcium phosphate (β TCP), and bioactive glasses. These regenerative materials not only act as an osteoconductive scaffold but also interact with the surrounding tissues and impart an osseostimulatory effect. METHODS: Twenty adult patients who required bilateral removal of homologous tooth, were informed and described regarding post extraction socket grafting using β TCP and CPS followed by covering with Collagen Membrane. Radiographic densitometry evaluation of postoperative visits of immediate; 1st month; 3rd month; and 6th month using orthopantomograph was done. RESULTS: The Karl Pearson's Correlation coefficient was used to determine the degree of bone density with adjacent bone preoperatively and postoperatively. The statistical evaluation, CPS was more superior to β TCP, with a difference of 58.75 and P value showed more significance (<0.0001). CONCLUSION: This article evaluates radiographically quality and quantity of bone formation in the socket, following extraction and bone grafting using Calcium Phosphosilicate (CPS) and β TCP, it is concluded that the two modalities of treatment were efficient in improving the clinical outcome parameters as well as showed comparable regenerative effects when used in the treatment of “socket grafting” while between them CPS more superior to β TCP biomaterials by Osteogenic properties.
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spelling pubmed-86869962022-01-10 A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study Saha, Alangkar Sathish, R. Setty, Suhas Maji, Abhijit Saha, Jayanta Chatterjee, Abhishek J Pharm Bioallied Sci Original Article BACKGROUND: Healing unbinds a well choreographed array of cellular, physiologic, biochemical, and molecular processes directed toward restoring the integrity and functional capacity of the damaged structures. The rate and degree of healing vary among individuals but is greatest during the first few months or years after tooth loss. Evidence suggests that alveolar bone ridge resorption may be prevented, initially by reconstructive surgical techniques using several materials which are employed at the time of extraction. This droves to the development of bone substitutes materials such as hydroxyapatite, beta tricalcium phosphate (β TCP), and bioactive glasses. These regenerative materials not only act as an osteoconductive scaffold but also interact with the surrounding tissues and impart an osseostimulatory effect. METHODS: Twenty adult patients who required bilateral removal of homologous tooth, were informed and described regarding post extraction socket grafting using β TCP and CPS followed by covering with Collagen Membrane. Radiographic densitometry evaluation of postoperative visits of immediate; 1st month; 3rd month; and 6th month using orthopantomograph was done. RESULTS: The Karl Pearson's Correlation coefficient was used to determine the degree of bone density with adjacent bone preoperatively and postoperatively. The statistical evaluation, CPS was more superior to β TCP, with a difference of 58.75 and P value showed more significance (<0.0001). CONCLUSION: This article evaluates radiographically quality and quantity of bone formation in the socket, following extraction and bone grafting using Calcium Phosphosilicate (CPS) and β TCP, it is concluded that the two modalities of treatment were efficient in improving the clinical outcome parameters as well as showed comparable regenerative effects when used in the treatment of “socket grafting” while between them CPS more superior to β TCP biomaterials by Osteogenic properties. Wolters Kluwer - Medknow 2021-11 2021-11-10 /pmc/articles/PMC8686996/ /pubmed/35017963 http://dx.doi.org/10.4103/jpbs.jpbs_409_21 Text en Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Saha, Alangkar
Sathish, R.
Setty, Suhas
Maji, Abhijit
Saha, Jayanta
Chatterjee, Abhishek
A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study
title A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study
title_full A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study
title_fullStr A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study
title_full_unstemmed A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study
title_short A Radiological Evaluation of Bone Healing in Postextraction Sockets Following Bone Grafting Using Beta-Tricalcium Phosphate and Calcium Phosphosilicate: A Controlled Comparative Study
title_sort radiological evaluation of bone healing in postextraction sockets following bone grafting using beta-tricalcium phosphate and calcium phosphosilicate: a controlled comparative study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686996/
https://www.ncbi.nlm.nih.gov/pubmed/35017963
http://dx.doi.org/10.4103/jpbs.jpbs_409_21
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