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Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh

BACKGROUND: Since August 2017, Myanmar nationals from Rakhine state have crossed the border into Bangladesh and settled in Cox’s Bazar, the World’s largest refugee camp. Due to overcrowding, poor sanitation, and hygienic practices they have been under significant health risks including diarrheal dis...

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Autores principales: Hossain, Mohammad Enayet, Islam, Md Muzahidul, Miah, Mojnu, Haque, Warda, Vinjé, Jan, Rahman, Mohammed Ziaur, Faruque, Abu Syed Golam, Khan, Azharul Islam, Ahmed, Tahmeed, Rahman, Mustafizur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687051/
https://www.ncbi.nlm.nih.gov/pubmed/34586390
http://dx.doi.org/10.1093/infdis/jiab466
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author Hossain, Mohammad Enayet
Islam, Md Muzahidul
Miah, Mojnu
Haque, Warda
Vinjé, Jan
Rahman, Mohammed Ziaur
Faruque, Abu Syed Golam
Khan, Azharul Islam
Ahmed, Tahmeed
Rahman, Mustafizur
author_facet Hossain, Mohammad Enayet
Islam, Md Muzahidul
Miah, Mojnu
Haque, Warda
Vinjé, Jan
Rahman, Mohammed Ziaur
Faruque, Abu Syed Golam
Khan, Azharul Islam
Ahmed, Tahmeed
Rahman, Mustafizur
author_sort Hossain, Mohammad Enayet
collection PubMed
description BACKGROUND: Since August 2017, Myanmar nationals from Rakhine state have crossed the border into Bangladesh and settled in Cox’s Bazar, the World’s largest refugee camp. Due to overcrowding, poor sanitation, and hygienic practices they have been under significant health risks including diarrheal diseases. The objective of this study is to determine the viral etiology of acute gastroenteritis (AGE) among forcibly displaced Myanmar nationals (FDMN) and adjacent Bangladeshi local host population (AHP). METHODS: From April 2018 to April 2019, we collected stool specimens from 764 FDMN and 1159 AHP of all ages. We tested 100 randomly selected specimens from each group for the most common AGE viruses. RESULTS: Among 200 diarrhea patients, 55% and 64% of FDMN and AHP patients, respectively, had viral infections; the most common viruses were rotavirus (29% vs 44%), adenovirus (24% vs 31%), and norovirus (14% vs 10%). In both populations, viral infections were significantly higher in children less than 5 years of age, compared with bacterial infections that were higher in patients older than 5 years of age (P ≤ .05). CONCLUSIONS: Disparities in viral and bacterial prevalence among various age groups warrant careful antibiotic usage, especially in children less than 5 years of age.
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spelling pubmed-86870512021-12-21 Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh Hossain, Mohammad Enayet Islam, Md Muzahidul Miah, Mojnu Haque, Warda Vinjé, Jan Rahman, Mohammed Ziaur Faruque, Abu Syed Golam Khan, Azharul Islam Ahmed, Tahmeed Rahman, Mustafizur J Infect Dis Enteric Diseases and Nutritional Disorders: Persisting Challenges for LMICs BACKGROUND: Since August 2017, Myanmar nationals from Rakhine state have crossed the border into Bangladesh and settled in Cox’s Bazar, the World’s largest refugee camp. Due to overcrowding, poor sanitation, and hygienic practices they have been under significant health risks including diarrheal diseases. The objective of this study is to determine the viral etiology of acute gastroenteritis (AGE) among forcibly displaced Myanmar nationals (FDMN) and adjacent Bangladeshi local host population (AHP). METHODS: From April 2018 to April 2019, we collected stool specimens from 764 FDMN and 1159 AHP of all ages. We tested 100 randomly selected specimens from each group for the most common AGE viruses. RESULTS: Among 200 diarrhea patients, 55% and 64% of FDMN and AHP patients, respectively, had viral infections; the most common viruses were rotavirus (29% vs 44%), adenovirus (24% vs 31%), and norovirus (14% vs 10%). In both populations, viral infections were significantly higher in children less than 5 years of age, compared with bacterial infections that were higher in patients older than 5 years of age (P ≤ .05). CONCLUSIONS: Disparities in viral and bacterial prevalence among various age groups warrant careful antibiotic usage, especially in children less than 5 years of age. Oxford University Press 2021-09-29 /pmc/articles/PMC8687051/ /pubmed/34586390 http://dx.doi.org/10.1093/infdis/jiab466 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Enteric Diseases and Nutritional Disorders: Persisting Challenges for LMICs
Hossain, Mohammad Enayet
Islam, Md Muzahidul
Miah, Mojnu
Haque, Warda
Vinjé, Jan
Rahman, Mohammed Ziaur
Faruque, Abu Syed Golam
Khan, Azharul Islam
Ahmed, Tahmeed
Rahman, Mustafizur
Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh
title Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh
title_full Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh
title_fullStr Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh
title_full_unstemmed Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh
title_short Viral Etiology of Acute Gastroenteritis Among Forcibly Displaced Myanmar Nationals and Adjacent Host Population in Bangladesh
title_sort viral etiology of acute gastroenteritis among forcibly displaced myanmar nationals and adjacent host population in bangladesh
topic Enteric Diseases and Nutritional Disorders: Persisting Challenges for LMICs
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687051/
https://www.ncbi.nlm.nih.gov/pubmed/34586390
http://dx.doi.org/10.1093/infdis/jiab466
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