Functional Antibodies and Innate Immune Responses to WRSS1, a Live Oral Shigella sonnei Vaccine Candidate, in Bangladeshi Adults and Children

BACKGROUND: We demonstrated in a randomized placebo-controlled trial that WRSS1, a live oral Shigella sonnei vaccine candidate, is safe in Bangladeshi adults and children, and elicits antigen-specific antibodies. Here, we describe functional antibody and innate immune responses to WRSS1. METHODS: Ad...

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Detalles Bibliográficos
Autores principales: Sarker, Protim, Mily, Akhirunnesa, Ara, Anjuman, Haque, Farjana, Maier, Nicole, Wierzba, Thomas F, Walker, Richard I, Venkatesan, Malabi M, Raqib, Rubhana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Enteric Diseases and Nutritional Disorders: Persisting Challenges for LMICs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687094/
https://www.ncbi.nlm.nih.gov/pubmed/34374425
http://dx.doi.org/10.1093/infdis/jiab395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687094/
https://www.ncbi.nlm.nih.gov/pubmed/34374425
http://dx.doi.org/10.1093/infdis/jiab395

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