Randomized controlled trial transfusing convalescent plasma as post-exposure prophylaxis against SARS-CoV-2 infection

BACKGROUND: The efficacy of SARS-CoV-2 convalescent plasma (CCP) for preventing infection in exposed, uninfected individuals is unknown. We hypothesized that CCP might prevent infection when administered before symptoms or laboratory evidence of infection. METHODS: This double-blinded, phase 2 rando...

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Detalles Bibliográficos
Autores principales: Shoham, Shmuel, Bloch, Evan M, Casadevall, Arturo, Hanley, Daniel, Lau, Bryan, Gebo, Kelly, Cachay, Edward, Kassaye, Seble G., Paxton, James H., Gerber, Jonathan, Levine, Adam C, Currier, Judith, Patel, Bela, Allen, Elizabeth S., Anjan, Shweta, Appel, Lawrence, Baksh, Sheriza, Blair, Paul W., Bowen, Anthony, Broderick, Patrick, Caputo, Christopher A, Cluzet, Valerie, Cordisco, Marie Elena, Cruser, Daniel, Ehrhardt, Stephan, Forthal, Donald, Fukuta, Yuriko, Gawad, Amy L., Gniadek, Thomas, Hammel, Jean, Huaman, Moises A., Jabs, Douglas A., Jedlicka, Anne, Karlen, Nicky, Klein, Sabra, Laeyendecker, Oliver, Lane, Karen, McBee, Nichol, Meisenberg, Barry, Merlo, Christian, Mosnaim, Giselle, Park, Han-Sol, Pekosz, Andrew, Petrini, Joann, Rausch, William, Shade, David M., Shapiro, Janna R., Singleton, J. Robinson, Sutcliffe, Catherine, Thomas, David L., Yarava, Anusha, Zand, Martin, Zenilman, Jonathan M., Tobian, Aaron A.R., Sullivan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687473/
https://www.ncbi.nlm.nih.gov/pubmed/34931202
http://dx.doi.org/10.1101/2021.12.13.21267611

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