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Seropositivity for Chagas disease in blood donors from the state of Alagoas, Northeastern Brazil: an 11-year time series study

INTRODUCTION: Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020. METHODS: Data were requested from the Alagoas blood center. Time trend analysis was performed using a joinpoint regression m...

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Detalles Bibliográficos
Autores principales: Abreu, Sílvia Letícia da Conceição, Bezerra-Santos, Márcio, Damasceno, Flávia Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687493/
https://www.ncbi.nlm.nih.gov/pubmed/34932762
http://dx.doi.org/10.1590/0037-8682-0339-2021
Descripción
Sumario:INTRODUCTION: Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020. METHODS: Data were requested from the Alagoas blood center. Time trend analysis was performed using a joinpoint regression model. RESULTS: Seropositivity rate during the study period was 0.35%, which decreased from 2014 to 2020, (annual percentage change, APC = -29.38; p-value <0.05), while the total number of tests performed remained stable (APC = 6.5). CONCLUSIONS: Despite the drop in the seropositivity for Chagas infection in donors, it is imperative to maintain the screening of donors for the epidemiological control.