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Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells
Ac3IV (Ac-CYIQNCPRG-NH(2)) is an enzymatically stable vasopressin analogue that selectively activates Avpr1a (V1a) and Avpr1b (V1b) receptors. In the current study we have employed streptozotocin (STZ) diabetic transgenic Ins1(Cre/+);Rosa26-eYFP and Glu(CreERT2);Rosa26-eYFP mice, to evaluate the imp...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687525/ https://www.ncbi.nlm.nih.gov/pubmed/34929019 http://dx.doi.org/10.1371/journal.pone.0261608 |