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Mean square displacement for a discrete centroid model of cell motion

The mean square displacement (MSD) is an important statistical measure on a stochastic process or a trajectory. In this paper we find an approximation to the mean square displacement for a model of cell motion. The model is a discrete-time jump process which approximates a force-based model for cell...

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Detalles Bibliográficos
Autores principales: Rosen, Mary Ellen, Grant, Christopher P., Dallon, J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687545/
https://www.ncbi.nlm.nih.gov/pubmed/34928985
http://dx.doi.org/10.1371/journal.pone.0261021
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author Rosen, Mary Ellen
Grant, Christopher P.
Dallon, J. C.
author_facet Rosen, Mary Ellen
Grant, Christopher P.
Dallon, J. C.
author_sort Rosen, Mary Ellen
collection PubMed
description The mean square displacement (MSD) is an important statistical measure on a stochastic process or a trajectory. In this paper we find an approximation to the mean square displacement for a model of cell motion. The model is a discrete-time jump process which approximates a force-based model for cell motion. In cell motion, the mean square displacement not only gives a measure of overall drift, but it is also an indicator of mode of transport. The key to finding the approximation is to find the mean square displacement for a subset of the state space and use it as an approximation for the entire state space. We give some intuition as to why this is an unexpectedly good approximation. A lower bound and upper bound for the mean square displacement are also given. We show that, although the upper bound is far from the computed mean square displacement, in rare cases the large displacements are approached.
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spelling pubmed-86875452021-12-21 Mean square displacement for a discrete centroid model of cell motion Rosen, Mary Ellen Grant, Christopher P. Dallon, J. C. PLoS One Research Article The mean square displacement (MSD) is an important statistical measure on a stochastic process or a trajectory. In this paper we find an approximation to the mean square displacement for a model of cell motion. The model is a discrete-time jump process which approximates a force-based model for cell motion. In cell motion, the mean square displacement not only gives a measure of overall drift, but it is also an indicator of mode of transport. The key to finding the approximation is to find the mean square displacement for a subset of the state space and use it as an approximation for the entire state space. We give some intuition as to why this is an unexpectedly good approximation. A lower bound and upper bound for the mean square displacement are also given. We show that, although the upper bound is far from the computed mean square displacement, in rare cases the large displacements are approached. Public Library of Science 2021-12-20 /pmc/articles/PMC8687545/ /pubmed/34928985 http://dx.doi.org/10.1371/journal.pone.0261021 Text en © 2021 Rosen et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Rosen, Mary Ellen
Grant, Christopher P.
Dallon, J. C.
Mean square displacement for a discrete centroid model of cell motion
title Mean square displacement for a discrete centroid model of cell motion
title_full Mean square displacement for a discrete centroid model of cell motion
title_fullStr Mean square displacement for a discrete centroid model of cell motion
title_full_unstemmed Mean square displacement for a discrete centroid model of cell motion
title_short Mean square displacement for a discrete centroid model of cell motion
title_sort mean square displacement for a discrete centroid model of cell motion
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687545/
https://www.ncbi.nlm.nih.gov/pubmed/34928985
http://dx.doi.org/10.1371/journal.pone.0261021
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