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Normal manual straight ahead pointing in Complex Regional Pain Syndrome

There is evidence to suggest that people with Complex Regional Pain Syndrome (CRPS) can have altered body representations and spatial cognition. One way of studying these cognitive functions is through manual straight ahead (MSA) pointing, in which participants are required to point straight ahead o...

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Autores principales: Vittersø, Axel D., Buckingham, Gavin, Ten Brink, Antonia F., Halicka, Monika, Proulx, Michael J., Bultitude, Janet H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687552/
https://www.ncbi.nlm.nih.gov/pubmed/34929004
http://dx.doi.org/10.1371/journal.pone.0261614
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author Vittersø, Axel D.
Buckingham, Gavin
Ten Brink, Antonia F.
Halicka, Monika
Proulx, Michael J.
Bultitude, Janet H.
author_facet Vittersø, Axel D.
Buckingham, Gavin
Ten Brink, Antonia F.
Halicka, Monika
Proulx, Michael J.
Bultitude, Janet H.
author_sort Vittersø, Axel D.
collection PubMed
description There is evidence to suggest that people with Complex Regional Pain Syndrome (CRPS) can have altered body representations and spatial cognition. One way of studying these cognitive functions is through manual straight ahead (MSA) pointing, in which participants are required to point straight ahead of their perceived body midline without visual feedback of the hand. We therefore compared endpoint errors from MSA pointing between people with CRPS (n = 17) and matched controls (n = 18), and examined the effect of the arm used (Side of Body; affected/non-dominant, non-affected/dominant). For all participants, pointing errors were biased towards the hand being used. We found moderate evidence of no difference between Groups on endpoint errors, and moderate evidence of no interaction with Side of Body. The differences in variability between Groups were non-significant/inconclusive. Correlational analyses showed no evidence of a relationship between MSA endpoint errors and clinical parameters (e.g. CRPS severity, duration, pain) or questionnaire measures (e.g. body representation, “neglect-like symptoms”, upper limb disability). This study is consistent with earlier findings of no difference between people with CRPS and controls on MSA endpoint errors, and is the first to provide statistical evidence of similar performance of these two groups. Our results do not support a relationship between clinical or self-reported measures (e.g. “neglect-like symptoms”) and any directional biases in MSA. Our findings may have implications for understanding neurocognitive changes in CRPS.
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spelling pubmed-86875522021-12-21 Normal manual straight ahead pointing in Complex Regional Pain Syndrome Vittersø, Axel D. Buckingham, Gavin Ten Brink, Antonia F. Halicka, Monika Proulx, Michael J. Bultitude, Janet H. PLoS One Research Article There is evidence to suggest that people with Complex Regional Pain Syndrome (CRPS) can have altered body representations and spatial cognition. One way of studying these cognitive functions is through manual straight ahead (MSA) pointing, in which participants are required to point straight ahead of their perceived body midline without visual feedback of the hand. We therefore compared endpoint errors from MSA pointing between people with CRPS (n = 17) and matched controls (n = 18), and examined the effect of the arm used (Side of Body; affected/non-dominant, non-affected/dominant). For all participants, pointing errors were biased towards the hand being used. We found moderate evidence of no difference between Groups on endpoint errors, and moderate evidence of no interaction with Side of Body. The differences in variability between Groups were non-significant/inconclusive. Correlational analyses showed no evidence of a relationship between MSA endpoint errors and clinical parameters (e.g. CRPS severity, duration, pain) or questionnaire measures (e.g. body representation, “neglect-like symptoms”, upper limb disability). This study is consistent with earlier findings of no difference between people with CRPS and controls on MSA endpoint errors, and is the first to provide statistical evidence of similar performance of these two groups. Our results do not support a relationship between clinical or self-reported measures (e.g. “neglect-like symptoms”) and any directional biases in MSA. Our findings may have implications for understanding neurocognitive changes in CRPS. Public Library of Science 2021-12-20 /pmc/articles/PMC8687552/ /pubmed/34929004 http://dx.doi.org/10.1371/journal.pone.0261614 Text en © 2021 Vittersø et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Vittersø, Axel D.
Buckingham, Gavin
Ten Brink, Antonia F.
Halicka, Monika
Proulx, Michael J.
Bultitude, Janet H.
Normal manual straight ahead pointing in Complex Regional Pain Syndrome
title Normal manual straight ahead pointing in Complex Regional Pain Syndrome
title_full Normal manual straight ahead pointing in Complex Regional Pain Syndrome
title_fullStr Normal manual straight ahead pointing in Complex Regional Pain Syndrome
title_full_unstemmed Normal manual straight ahead pointing in Complex Regional Pain Syndrome
title_short Normal manual straight ahead pointing in Complex Regional Pain Syndrome
title_sort normal manual straight ahead pointing in complex regional pain syndrome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687552/
https://www.ncbi.nlm.nih.gov/pubmed/34929004
http://dx.doi.org/10.1371/journal.pone.0261614
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