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Modelling RT-qPCR cycle-threshold using digital PCR data for implementing SARS-CoV-2 viral load studies

OBJECTIVES: To exploit the features of digital PCR for implementing SARS-CoV-2 observational studies by reliably including the viral load factor expressed as copies/μL. METHODS: A small cohort of 51 Covid-19 positive samples was assessed by both RT-qPCR and digital PCR assays. A linear regression mo...

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Detalles Bibliográficos
Autores principales: Gentilini, Fabio, Turba, Maria Elena, Taddei, Francesca, Gritti, Tommaso, Fantini, Michela, Dirani, Giorgio, Sambri, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687578/
https://www.ncbi.nlm.nih.gov/pubmed/34928966
http://dx.doi.org/10.1371/journal.pone.0260884

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