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Modelling RT-qPCR cycle-threshold using digital PCR data for implementing SARS-CoV-2 viral load studies
OBJECTIVES: To exploit the features of digital PCR for implementing SARS-CoV-2 observational studies by reliably including the viral load factor expressed as copies/μL. METHODS: A small cohort of 51 Covid-19 positive samples was assessed by both RT-qPCR and digital PCR assays. A linear regression mo...
Autores principales: | Gentilini, Fabio, Turba, Maria Elena, Taddei, Francesca, Gritti, Tommaso, Fantini, Michela, Dirani, Giorgio, Sambri, Vittorio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687578/ https://www.ncbi.nlm.nih.gov/pubmed/34928966 http://dx.doi.org/10.1371/journal.pone.0260884 |
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