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FaDA: A web application for regular laboratory data analyses
Web-based data analysis and visualization tools are mostly designed for specific purposes, such as the analysis of data from whole transcriptome RNA sequencing or single-cell RNA sequencing. However, generic tools designed for the analysis of common laboratory data for noncomputational scientists ar...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687579/ https://www.ncbi.nlm.nih.gov/pubmed/34928943 http://dx.doi.org/10.1371/journal.pone.0261083 |
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author | Danger, Richard Moiteaux, Quentin Feseha, Yodit Geffard, Estelle Ramstein, Gérard Brouard, Sophie |
author_facet | Danger, Richard Moiteaux, Quentin Feseha, Yodit Geffard, Estelle Ramstein, Gérard Brouard, Sophie |
author_sort | Danger, Richard |
collection | PubMed |
description | Web-based data analysis and visualization tools are mostly designed for specific purposes, such as the analysis of data from whole transcriptome RNA sequencing or single-cell RNA sequencing. However, generic tools designed for the analysis of common laboratory data for noncomputational scientists are also needed. The importance of such web-based tools is emphasized by the continuing increases in the sample capacity of conventional laboratory tools such as quantitative PCR, flow cytometry or ELISA instruments. We present a web-based application FaDA, developed with the R Shiny package that provides users with the ability to perform statistical group comparisons, including parametric and nonparametric tests, with multiple testing corrections suitable for most standard wet-laboratory analyses. FaDA provides data visualizations such as heatmaps, principal component analysis (PCA) plots, correlograms and receiver operating curves (ROCs). Calculations are performed through the R language. The FaDA application provides a free and intuitive interface that allows biologists without bioinformatic skill to easily and quickly perform common laboratory data analyses. The application is freely accessible at https://shiny-bird.univ-nantes.fr/app/Fada. |
format | Online Article Text |
id | pubmed-8687579 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-86875792021-12-21 FaDA: A web application for regular laboratory data analyses Danger, Richard Moiteaux, Quentin Feseha, Yodit Geffard, Estelle Ramstein, Gérard Brouard, Sophie PLoS One Research Article Web-based data analysis and visualization tools are mostly designed for specific purposes, such as the analysis of data from whole transcriptome RNA sequencing or single-cell RNA sequencing. However, generic tools designed for the analysis of common laboratory data for noncomputational scientists are also needed. The importance of such web-based tools is emphasized by the continuing increases in the sample capacity of conventional laboratory tools such as quantitative PCR, flow cytometry or ELISA instruments. We present a web-based application FaDA, developed with the R Shiny package that provides users with the ability to perform statistical group comparisons, including parametric and nonparametric tests, with multiple testing corrections suitable for most standard wet-laboratory analyses. FaDA provides data visualizations such as heatmaps, principal component analysis (PCA) plots, correlograms and receiver operating curves (ROCs). Calculations are performed through the R language. The FaDA application provides a free and intuitive interface that allows biologists without bioinformatic skill to easily and quickly perform common laboratory data analyses. The application is freely accessible at https://shiny-bird.univ-nantes.fr/app/Fada. Public Library of Science 2021-12-20 /pmc/articles/PMC8687579/ /pubmed/34928943 http://dx.doi.org/10.1371/journal.pone.0261083 Text en © 2021 Danger et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Danger, Richard Moiteaux, Quentin Feseha, Yodit Geffard, Estelle Ramstein, Gérard Brouard, Sophie FaDA: A web application for regular laboratory data analyses |
title | FaDA: A web application for regular laboratory data analyses |
title_full | FaDA: A web application for regular laboratory data analyses |
title_fullStr | FaDA: A web application for regular laboratory data analyses |
title_full_unstemmed | FaDA: A web application for regular laboratory data analyses |
title_short | FaDA: A web application for regular laboratory data analyses |
title_sort | fada: a web application for regular laboratory data analyses |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687579/ https://www.ncbi.nlm.nih.gov/pubmed/34928943 http://dx.doi.org/10.1371/journal.pone.0261083 |
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