Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), whi...

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Autores principales: Fajardo, Álvaro, Perbolianachis, Paula, Ferreiro, Irene, Moreno, Pilar, Moratorio, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687762/
https://www.ncbi.nlm.nih.gov/pubmed/35042168
http://dx.doi.org/10.1016/j.coph.2021.12.006
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author Fajardo, Álvaro
Perbolianachis, Paula
Ferreiro, Irene
Moreno, Pilar
Moratorio, Gonzalo
author_facet Fajardo, Álvaro
Perbolianachis, Paula
Ferreiro, Irene
Moreno, Pilar
Moratorio, Gonzalo
author_sort Fajardo, Álvaro
collection PubMed
description The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs.
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spelling pubmed-86877622021-12-21 Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies Fajardo, Álvaro Perbolianachis, Paula Ferreiro, Irene Moreno, Pilar Moratorio, Gonzalo Curr Opin Pharmacol Article The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs. Published by Elsevier Ltd. 2022-02 2021-12-21 /pmc/articles/PMC8687762/ /pubmed/35042168 http://dx.doi.org/10.1016/j.coph.2021.12.006 Text en © 2022 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Fajardo, Álvaro
Perbolianachis, Paula
Ferreiro, Irene
Moreno, Pilar
Moratorio, Gonzalo
Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies
title Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies
title_full Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies
title_fullStr Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies
title_full_unstemmed Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies
title_short Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies
title_sort molecular accuracy vs antigenic speed: sars-cov-2 testing strategies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687762/
https://www.ncbi.nlm.nih.gov/pubmed/35042168
http://dx.doi.org/10.1016/j.coph.2021.12.006
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