A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently

Apixaban, a direct oral anticoagulant, has been demonstrated to increase the risk of bleeding in individuals with atrial fibrillation when used concurrently with citalopram [selective serotonin reuptake inhibitor (SSRI)]. This was proposed as a result of their synergistic anticoagulant effects. We d...

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Detalles Bibliográficos
Autores principales: Datta, Sorabh, Mahal, Karan, Mahal, Shanan, Driskill, Angela K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687801/
https://www.ncbi.nlm.nih.gov/pubmed/34950549
http://dx.doi.org/10.7759/cureus.19771
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author Datta, Sorabh
Mahal, Karan
Mahal, Shanan
Driskill, Angela K
author_facet Datta, Sorabh
Mahal, Karan
Mahal, Shanan
Driskill, Angela K
author_sort Datta, Sorabh
collection PubMed
description Apixaban, a direct oral anticoagulant, has been demonstrated to increase the risk of bleeding in individuals with atrial fibrillation when used concurrently with citalopram [selective serotonin reuptake inhibitor (SSRI)]. This was proposed as a result of their synergistic anticoagulant effects. We discuss a rare case in which a limb-threatening hematoma was noticed in an 85-year-old female patient who was just begun on citalopram and was on apixaban. There are few published case studies demonstrating a link between these two kinds of drugs, and our case study aims to inform our audience about the possible negative effects of concurrent usage of these two medications.
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spelling pubmed-86878012021-12-22 A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently Datta, Sorabh Mahal, Karan Mahal, Shanan Driskill, Angela K Cureus Cardiology Apixaban, a direct oral anticoagulant, has been demonstrated to increase the risk of bleeding in individuals with atrial fibrillation when used concurrently with citalopram [selective serotonin reuptake inhibitor (SSRI)]. This was proposed as a result of their synergistic anticoagulant effects. We discuss a rare case in which a limb-threatening hematoma was noticed in an 85-year-old female patient who was just begun on citalopram and was on apixaban. There are few published case studies demonstrating a link between these two kinds of drugs, and our case study aims to inform our audience about the possible negative effects of concurrent usage of these two medications. Cureus 2021-11-20 /pmc/articles/PMC8687801/ /pubmed/34950549 http://dx.doi.org/10.7759/cureus.19771 Text en Copyright © 2021, Datta et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Datta, Sorabh
Mahal, Karan
Mahal, Shanan
Driskill, Angela K
A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently
title A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently
title_full A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently
title_fullStr A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently
title_full_unstemmed A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently
title_short A Case of Limb-Threatening Hematoma in a Patient Taking Citalopram and Apixaban Concurrently
title_sort case of limb-threatening hematoma in a patient taking citalopram and apixaban concurrently
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687801/
https://www.ncbi.nlm.nih.gov/pubmed/34950549
http://dx.doi.org/10.7759/cureus.19771
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