The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice

Ageing-associated functional decline of organs and increased risk for age-related chronic pathologies is driven in part by the accumulation of senescent cells, which develop the senescence-associated secretory phenotype (SASP). Here we show that procyanidin C1 (PCC1), a polyphenolic component of gra...

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Detalles Bibliográficos
Autores principales: Xu, Qixia, Fu, Qiang, Li, Zi, Liu, Hanxin, Wang, Ying, Lin, Xu, He, Ruikun, Zhang, Xuguang, Ju, Zhenyu, Campisi, Judith, Kirkland, James L., Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688144/
https://www.ncbi.nlm.nih.gov/pubmed/34873338
http://dx.doi.org/10.1038/s42255-021-00491-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688144/
https://www.ncbi.nlm.nih.gov/pubmed/34873338
http://dx.doi.org/10.1038/s42255-021-00491-8

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