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NLPR3 inflammasome inhibition alleviates hypoxic endothelial cell death in vitro and protects blood–brain barrier integrity in murine stroke

In ischemic stroke (IS) impairment of the blood–brain barrier (BBB) has an important role in the secondary deterioration of neurological function. BBB disruption is associated with ischemia-induced inflammation, brain edema formation, and hemorrhagic infarct transformation, but the underlying mechan...

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Detalles Bibliográficos
Autores principales:	Bellut, Maximilian, Papp, Lena, Bieber, Michael, Kraft, Peter, Stoll, Guido, Schuhmann, Michael K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688414/ https://www.ncbi.nlm.nih.gov/pubmed/34930895 http://dx.doi.org/10.1038/s41419-021-04379-z

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