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Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children

To identify and compare keratometric, corneal thickness, and elevation parameters and indices among healthy children, ocular allergy, and keratoconus using the OCULUS Pentacam Scheimpflug topography system. This study included healthy children, children with ocular allergy (OA) without keratoconus,...

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Autores principales: Vieira, Matheus Ivan Schmitz, Jammal, Alessandro Adad, Arieta, Carlos Eduardo Leite, Alves, Monica, de Vasconcellos, Jose Paulo Cabral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688439/
https://www.ncbi.nlm.nih.gov/pubmed/34931010
http://dx.doi.org/10.1038/s41598-021-03818-3
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author Vieira, Matheus Ivan Schmitz
Jammal, Alessandro Adad
Arieta, Carlos Eduardo Leite
Alves, Monica
de Vasconcellos, Jose Paulo Cabral
author_facet Vieira, Matheus Ivan Schmitz
Jammal, Alessandro Adad
Arieta, Carlos Eduardo Leite
Alves, Monica
de Vasconcellos, Jose Paulo Cabral
author_sort Vieira, Matheus Ivan Schmitz
collection PubMed
description To identify and compare keratometric, corneal thickness, and elevation parameters and indices among healthy children, ocular allergy, and keratoconus using the OCULUS Pentacam Scheimpflug topography system. This study included healthy children, children with ocular allergy (OA) without keratoconus, and children with keratoconus (KC). The study design consisted of a prospective evaluation and review of medical records from a Brazilian ophthalmology department. The exclusion criteria were inability to undergo the ocular exam, other ocular diseases, contact lens wear, and topographic corneal ectasia. The effect of each corneal parameter was evaluated using univariate and multivariate logistic regression models adjusted for sex and age, and ROC curves were used to assess the ability each variable to discriminate among groups. A total of 182 subjects were included: healthy children (n = 99), children with OA (n = 32), and children with KC (n = 51). Groups differed in terms of sex, with more males in the OA group (73.2%) and the KC group (67.7%) than in the control group (40.9%). All corneal parameters studied differed significantly between the control and KC groups, and between the OA and KC groups; they also differed significantly between the three groups in terms of astigmatism, q-value, CCT, TP, BAD-D, and ARTmax values. We present the first study to describe and compare corneal tomographic parameters in healthy children, OA, and KC. Keratometry indices, ACD, ARTmax, AETP, and PETP were found to be the most useful for differentiating between healthy and KC children. IBR registry number: CAAE 54921916.9.0000.5404.
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spelling pubmed-86884392021-12-22 Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children Vieira, Matheus Ivan Schmitz Jammal, Alessandro Adad Arieta, Carlos Eduardo Leite Alves, Monica de Vasconcellos, Jose Paulo Cabral Sci Rep Article To identify and compare keratometric, corneal thickness, and elevation parameters and indices among healthy children, ocular allergy, and keratoconus using the OCULUS Pentacam Scheimpflug topography system. This study included healthy children, children with ocular allergy (OA) without keratoconus, and children with keratoconus (KC). The study design consisted of a prospective evaluation and review of medical records from a Brazilian ophthalmology department. The exclusion criteria were inability to undergo the ocular exam, other ocular diseases, contact lens wear, and topographic corneal ectasia. The effect of each corneal parameter was evaluated using univariate and multivariate logistic regression models adjusted for sex and age, and ROC curves were used to assess the ability each variable to discriminate among groups. A total of 182 subjects were included: healthy children (n = 99), children with OA (n = 32), and children with KC (n = 51). Groups differed in terms of sex, with more males in the OA group (73.2%) and the KC group (67.7%) than in the control group (40.9%). All corneal parameters studied differed significantly between the control and KC groups, and between the OA and KC groups; they also differed significantly between the three groups in terms of astigmatism, q-value, CCT, TP, BAD-D, and ARTmax values. We present the first study to describe and compare corneal tomographic parameters in healthy children, OA, and KC. Keratometry indices, ACD, ARTmax, AETP, and PETP were found to be the most useful for differentiating between healthy and KC children. IBR registry number: CAAE 54921916.9.0000.5404. Nature Publishing Group UK 2021-12-20 /pmc/articles/PMC8688439/ /pubmed/34931010 http://dx.doi.org/10.1038/s41598-021-03818-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Vieira, Matheus Ivan Schmitz
Jammal, Alessandro Adad
Arieta, Carlos Eduardo Leite
Alves, Monica
de Vasconcellos, Jose Paulo Cabral
Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children
title Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children
title_full Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children
title_fullStr Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children
title_full_unstemmed Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children
title_short Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children
title_sort corneal scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688439/
https://www.ncbi.nlm.nih.gov/pubmed/34931010
http://dx.doi.org/10.1038/s41598-021-03818-3
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