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Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM

The emergence of SARS-CoV-2 Kappa and Beta variants with enhanced transmissibility and resistance to neutralizing antibodies has created new challenges for the control of the ongoing COVID-19 pandemic. Understanding the structural nature of Kappa and Beta spike (S) proteins and their association wit...

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Detalles Bibliográficos
Autores principales: Wang, Yifan, Xu, Cong, Wang, Yanxing, Hong, Qin, Zhang, Chao, Li, Zuyang, Xu, Shiqi, Zuo, Qinyu, Liu, Caixuan, Huang, Zhong, Cong, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688474/
https://www.ncbi.nlm.nih.gov/pubmed/34930910
http://dx.doi.org/10.1038/s41467-021-27350-0