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An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method

Many numerical studies of blood flow impose a rigid wall assumption due to the simplicity of its implementation compared to a full coupling with a solid mechanics model. In this paper, we present a localised method for incorporating the effects of elastic walls into blood flow simulations using the...

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Detalles Bibliográficos
Autores principales: McCullough, J. W. S., Coveney, P. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688478/
https://www.ncbi.nlm.nih.gov/pubmed/34930939
http://dx.doi.org/10.1038/s41598-021-03584-2
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author McCullough, J. W. S.
Coveney, P. V.
author_facet McCullough, J. W. S.
Coveney, P. V.
author_sort McCullough, J. W. S.
collection PubMed
description Many numerical studies of blood flow impose a rigid wall assumption due to the simplicity of its implementation compared to a full coupling with a solid mechanics model. In this paper, we present a localised method for incorporating the effects of elastic walls into blood flow simulations using the lattice Boltzmann method implemented by the open-source code HemeLB. We demonstrate that our approach is able to more accurately capture the flow behaviour expected in elastic walled vessels than ones with rigid walls. Furthermore, we show that this can be achieved with no loss of computational performance and remains strongly scalable on high performance computers. We finally illustrate that our approach captures the same trends in wall shear stress distribution as those observed in studies using a rigorous coupling between fluid dynamics and solid mechanics models to solve flow in personalised vascular geometries. These results demonstrate that our model can be used to efficiently and effectively represent flows in elastic blood vessels.
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spelling pubmed-86884782021-12-22 An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method McCullough, J. W. S. Coveney, P. V. Sci Rep Article Many numerical studies of blood flow impose a rigid wall assumption due to the simplicity of its implementation compared to a full coupling with a solid mechanics model. In this paper, we present a localised method for incorporating the effects of elastic walls into blood flow simulations using the lattice Boltzmann method implemented by the open-source code HemeLB. We demonstrate that our approach is able to more accurately capture the flow behaviour expected in elastic walled vessels than ones with rigid walls. Furthermore, we show that this can be achieved with no loss of computational performance and remains strongly scalable on high performance computers. We finally illustrate that our approach captures the same trends in wall shear stress distribution as those observed in studies using a rigorous coupling between fluid dynamics and solid mechanics models to solve flow in personalised vascular geometries. These results demonstrate that our model can be used to efficiently and effectively represent flows in elastic blood vessels. Nature Publishing Group UK 2021-12-20 /pmc/articles/PMC8688478/ /pubmed/34930939 http://dx.doi.org/10.1038/s41598-021-03584-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
McCullough, J. W. S.
Coveney, P. V.
An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method
title An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method
title_full An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method
title_fullStr An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method
title_full_unstemmed An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method
title_short An efficient, localised approach for the simulation of elastic blood vessels using the lattice Boltzmann method
title_sort efficient, localised approach for the simulation of elastic blood vessels using the lattice boltzmann method
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688478/
https://www.ncbi.nlm.nih.gov/pubmed/34930939
http://dx.doi.org/10.1038/s41598-021-03584-2
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