Single cell RNA sequencing reveals ferritin as a key mediator of autoimmune pre-disposition in a mouse model of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a devastating autoimmune disorder characterized by failure of self-tolerance with resultant production of autoreactive antibodies. The etiology of this syndrome is complex, involving perturbations in immune cell signaling and development. The NZBWF1 mouse sponta...

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Detalles Bibliográficos
Autores principales: Younes, Subhi Talal, Showmaker, Kurt, Johnson, Ashley C., Garrett, Michael R., Ryan, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688484/
https://www.ncbi.nlm.nih.gov/pubmed/34930978
http://dx.doi.org/10.1038/s41598-021-03649-2

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