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Assessments of different batches and dose levels of a two-dose Ad26.ZEBOV and MVA-BN-Filo vaccine regimen

Two phase 3 clinical studies were conducted in the USA to bridge across different Ad26.ZEBOV manufacturing processes and sites, and to evaluate the immunogenicity of different dose levels of Ad26.ZEBOV and MVA-BN-Filo. Study 1 evaluated the immunological equivalence of three batches of Ad26.ZEBOV ad...

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Detalles Bibliográficos
Autores principales: Bockstal, Viki, Gaddah, Auguste, Goldstein, Neil, Shukarev, Georgi, Bart, Stephan, Luhn, Kerstin, Robinson, Cynthia, Anumendem, Dickson, Leyssen, Maarten, Douoguih, Macaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688528/
https://www.ncbi.nlm.nih.gov/pubmed/34930928
http://dx.doi.org/10.1038/s41541-021-00402-8