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SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice via NF-ĸB Activation

BACKGROUND: Infection of SARS-CoV-2 may cause acute respiratory syndrome. It has been reported that SARS-CoV-2 nucleocapsid protein (N-protein) presents early in body fluids during infection. The direct involvement of N-protein in lung injury is poorly understood. METHODS: Recombinant N-protein was...

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Detalles Bibliográficos
Autores principales:	Xia, Jie, Tang, Wenqi, Wang, Jiangmei, Lai, Dengming, Xu, Qi, Huang, Ruoqiong, Hu, Yaoqin, Gong, Xiaojue, Fan, Jiajie, Shu, Qiang, Xu, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688532/ https://www.ncbi.nlm.nih.gov/pubmed/34950152 http://dx.doi.org/10.3389/fimmu.2021.791753

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