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Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease
BACKGROUND: Loss of intestinal epithelial barrier integrity is a critical component of Inflammatory Bowel Disease (IBD) pathogenesis. Co-expression regulation of ligand-receptor pairs in IBD mucosa has not been systematically studied. Targeting ligand-receptor pairs which are induced in IBD mucosa a...
Autores principales: | Cheng, Yang, Hall, Tyler R., Xu, Xiao, Yung, Ivy, Souza, Donald, Zheng, Jie, Schiele, Felix, Hoffmann, Matthias, Mbow, M. Lamine, Garnett, James P., Li, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688562/ https://www.ncbi.nlm.nih.gov/pubmed/34933179 http://dx.doi.org/10.1016/j.ebiom.2021.103758 |
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