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The Chemokine Receptor CCR5 Links Memory CD4(+) T Cell Metabolism to T Cell Antigen Receptor Nanoclustering
The inhibition of anabolic pathways, such as aerobic glycolysis, is a metabolic cornerstone of memory T cell differentiation and function. However, the signals that hamper these anabolic pathways are not completely known. Recent evidence pinpoints the chemokine receptor CCR5 as an important player i...
Autores principales: | Blanco, Raquel, Gómez de Cedrón, Marta, Gámez-Reche, Laura, Martín-Leal, Ana, González-Martín, Alicia, Lacalle, Rosa A., Ramírez de Molina, Ana, Mañes, Santos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688711/ https://www.ncbi.nlm.nih.gov/pubmed/34950130 http://dx.doi.org/10.3389/fimmu.2021.722320 |
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