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Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids

BACKGROUND & AIMS: Liver and bile duct diseases often are associated with extensive cell death of cholangiocytes. Necroptosis represents a common mode of programmed cell death in cholangiopathy, however, detailed mechanistic knowledge is limited owing to the lack of appropriate in vitro models....

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Detalles Bibliográficos
Autores principales: Shi, Shaojun, Verstegen, Monique M.A., Roest, Henk P., Ardisasmita, Arif I., Cao, Wanlu, Roos, Floris J.M., de Ruiter, Petra E., Niemeijer, Marije, Pan, Qiuwei, IJzermans, Jan N.M., van der Laan, Luc J.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688721/
https://www.ncbi.nlm.nih.gov/pubmed/34700031
http://dx.doi.org/10.1016/j.jcmgh.2021.10.009