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Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer

BACKGROUND & AIMS: Patient-derived tumor organoids recapitulate the characteristics of colorectal cancer (CRC) and provide an ideal platform for preclinical evaluation of personalized treatment options. We aimed to model the acquisition of chemotolerance during first-line combination chemotherap...

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Detalles Bibliográficos
Autores principales:	Boos, Sophie L., Loevenich, Leon P., Vosberg, Sebastian, Engleitner, Thomas, Öllinger, Rupert, Kumbrink, Jörg, Rokavec, Matjaz, Michl, Marlies, Greif, Philipp A., Jung, Andreas, Hermeking, Heiko, Neumann, Jens, Kirchner, Thomas, Rad, Roland, Jung, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688726/ https://www.ncbi.nlm.nih.gov/pubmed/34700030 http://dx.doi.org/10.1016/j.jcmgh.2021.10.008

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