NF-κB/p65 Competes With Peroxisome Proliferator-Activated Receptor Gamma for Transient Receptor Potential Channel 6 in Hypoxia-Induced Human Pulmonary Arterial Smooth Muscle Cells

Objective: Peroxisome proliferator-activated receptor gamma (PPARγ) has an anti-proliferation effect on pulmonary arterial smooth muscle cells (PASMCs) via the transient receptor potential channel (TRPC) and protects against pulmonary artery hypertension (PAH), whereas nuclear factor-kappa B (NF-κB)...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Li, Naijian, Wang, Yingfeng, Zheng, Guobing, An, Jing, Liu, Chang, Wang, Yajie, Liu, Qicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688744/
https://www.ncbi.nlm.nih.gov/pubmed/34950652
http://dx.doi.org/10.3389/fcell.2021.656625

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