TMB and TCR Are Correlated Indicators Predictive of the Efficacy of Neoadjuvant Chemotherapy in Breast Cancer

Immune characteristics were reported correlated to benefit neoadjuvant chemotherapy (NAC) in breast cancer, yet integration of comprehensive genomic alterations and T-cell receptors (TCR) to predict efficacy of NAC needs further investigation. This study simultaneously analyzed TMB (Tumor Mutation B...

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Detalles Bibliográficos
Autores principales: Liang, Hongling, Huang, Jia, Ao, Xiang, Guo, Weibang, Chen, Yu, Lu, Danxia, Lv, Zhiyi, Tan, Xiaojun, He, Weixing, Jiang, Ming, Xia, Haoming, Zhan, Yongtao, Guo, Weiling, Ye, Zhiqing, Jiao, Lei, Ma, Jie, Wang, Changxi, Li, Hongsheng, Zhang, Xuchao, Huang, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688823/
https://www.ncbi.nlm.nih.gov/pubmed/34950580
http://dx.doi.org/10.3389/fonc.2021.740427

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