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Weight Loss in Cancer Patients Correlates With p38β MAPK Activation in Skeletal Muscle

Unintentional weight loss, a first clinical sign of muscle wasting, is a major threat to cancer survival without a defined etiology. We previously identified in mice that p38β MAPK mediates cancer-induced muscle wasting by stimulating protein catabolism. However, whether this mechanism is relevant t...

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Detalles Bibliográficos
Autores principales: Zhang, Guohua, Anderson, Lindsey J., Gao, Song, Sin, Thomas K., Zhang, Zicheng, Wu, Hongyu, Jafri, Syed H., Graf, Solomon A., Wu, Peter C., Dash, Atreya, Garcia, Jose M., Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688918/
https://www.ncbi.nlm.nih.gov/pubmed/34950660
http://dx.doi.org/10.3389/fcell.2021.784424