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Analysis of Mitochondrial Calcium Retention Capacity in Cultured Cells: Permeabilized Cells Versus Isolated Mitochondria

In response to various pathological stimuli, such as oxidative and energy stress accompanied by high Ca(2+), mitochondria undergo permeability transition (PT) leading to the opening of the non-selective PT pores (PTP) in the inner mitochondrial membrane. Opening of the pores at high conductance allo...

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Detalles Bibliográficos
Autores principales: Jang, Sehwan, Chapa-Dubocq, Xavier R., Fossati, Silvia, Javadov, Sabzali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688924/
https://www.ncbi.nlm.nih.gov/pubmed/34950052
http://dx.doi.org/10.3389/fphys.2021.773839