Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report

Erdheim–Chester disease is a rare multisystemic non-Langerhans histiocytosis characterized by histiocytes that stain positive for CD68 and negative for CD1a. Skeletal involvement is reported to be present in up to 96% cases and BRAF mutation in about half of the cases. Here, we report a patient with...

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Autores principales: Kanza, Rene Epunza, Houle, Olivier, Simard, Pierre-Luc, St-Gelais, Jonathan, Raymond, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688944/
https://www.ncbi.nlm.nih.gov/pubmed/34976258
http://dx.doi.org/10.1016/j.radcr.2021.11.056
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author Kanza, Rene Epunza
Houle, Olivier
Simard, Pierre-Luc
St-Gelais, Jonathan
Raymond, Catherine
author_facet Kanza, Rene Epunza
Houle, Olivier
Simard, Pierre-Luc
St-Gelais, Jonathan
Raymond, Catherine
author_sort Kanza, Rene Epunza
collection PubMed
description Erdheim–Chester disease is a rare multisystemic non-Langerhans histiocytosis characterized by histiocytes that stain positive for CD68 and negative for CD1a. Skeletal involvement is reported to be present in up to 96% cases and BRAF mutation in about half of the cases. Here, we report a patient with an unusual longstanding BRAF-negative Erdheim–Chester disease without bone lesions who developed pleuropulmonary and cardiac involvement.
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spelling pubmed-86889442021-12-30 Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report Kanza, Rene Epunza Houle, Olivier Simard, Pierre-Luc St-Gelais, Jonathan Raymond, Catherine Radiol Case Rep Case Report Erdheim–Chester disease is a rare multisystemic non-Langerhans histiocytosis characterized by histiocytes that stain positive for CD68 and negative for CD1a. Skeletal involvement is reported to be present in up to 96% cases and BRAF mutation in about half of the cases. Here, we report a patient with an unusual longstanding BRAF-negative Erdheim–Chester disease without bone lesions who developed pleuropulmonary and cardiac involvement. Elsevier 2021-12-16 /pmc/articles/PMC8688944/ /pubmed/34976258 http://dx.doi.org/10.1016/j.radcr.2021.11.056 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kanza, Rene Epunza
Houle, Olivier
Simard, Pierre-Luc
St-Gelais, Jonathan
Raymond, Catherine
Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report
title Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report
title_full Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report
title_fullStr Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report
title_full_unstemmed Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report
title_short Cardiac and pleuropulmonary involvement in Erdheim-Chester disease without bone lesions: A case report
title_sort cardiac and pleuropulmonary involvement in erdheim-chester disease without bone lesions: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688944/
https://www.ncbi.nlm.nih.gov/pubmed/34976258
http://dx.doi.org/10.1016/j.radcr.2021.11.056
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