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Dual-targeting vaccine of FGL1/CAIX exhibits potent anti-tumor activity by activating DC-mediated multi-functional CD8 T cell immunity

Tumor DNA vaccine as an effective therapeutic approach can induce systemic immunity against malignant tumors, but its therapeutic effect is still not satisfactory in advanced renal cancer. Herein, a novel DNA vaccine containing dual antigens of fibrinogen-like protein 1 (FGL1) and carbonic anhydrase...

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Detalles Bibliográficos
Autores principales:	Chai, Dafei, Qiu, Dong, Shi, Xiaoqing, Ding, Jiage, Jiang, Nan, Zhang, Zichun, Wang, Jiawei, Yang, Jie, Xiao, Pengli, Wang, Gang, Zheng, Junnian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688948/ https://www.ncbi.nlm.nih.gov/pubmed/34977338 http://dx.doi.org/10.1016/j.omto.2021.11.017

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