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Intra-Tumor Heterogeneity of Colorectal Cancer Necessitates the Multi-Regional Sequencing for Comprehensive Mutational Profiling

BACKGROUND: The panorama and details of quantitative intratumor heterogeneity have not been fully investigated in colorectal cancer (CRC) patients with solitary lesion without distal metastasis, and its influences on sequencing interpretation and therapeutic strategies have not been explored. METHOD...

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Detalles Bibliográficos
Autores principales:	Guo, Shaohua, Ye, Yumeng, Liu, Xinyi, Gong, Yuan, Xu, Mingyan, Song, Lele, Liu, Hongyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689048/ https://www.ncbi.nlm.nih.gov/pubmed/34949941 http://dx.doi.org/10.2147/CMAR.S327596

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