DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus

Pathogens including autoantigens all failed to induce systemic lupus erythematosus (SLE). We, instead, studied the integrity of host's immune response that recognized pathogen. By stimulating TCR with an antigen repeatedly to levels that surpass host's steady-state response, self-organized...

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Detalles Bibliográficos
Autores principales: Shiozawa, Shunichi, Tsumiyama, Ken, Miyazaki, Yumi, Uto, Kenichi, Sakurai, Keiichi, Nakashima, Toshie, Matsuyama, Hiroko, Doi, Ai, Tarui, Miho, Izumikawa, Manabu, Kimura, Mai, Fujita, Yuko, Satonaka, Chisako, Horiuchi, Takahiko, Matsubara, Tsukasa, Oribe, Motohiro, Yamane, Takashi, Kagawa, Hidetoshi, Li, Quan-Zhen, Mizuno, Keiko, Mukai, Yohei, Murakami, Kazuhiro, Enya, Takuji, Tsukimoto, Shota, Hakata, Yoshiyuki, Miyazawa, Masaaki, Shiozawa, Kazuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689056/
https://www.ncbi.nlm.nih.gov/pubmed/34977502
http://dx.doi.org/10.1016/j.isci.2021.103537

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