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Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy

PURPOSE: To investigate the clinical outcomes following meniscus allograft transplantation (MAT) to replace removed discoid lateral meniscus using intact lateral meniscus obtained from patients undergoing total knee arthroplasty for medial compartment osteoarthritis. METHODS: Pediatric patients who...

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Autores principales: Kimura, Yuka, Yamamoto, Yuji, Sasaki, Shizuka, Sasaki, Eiji, Sasaki, Tomoyuki, Tsuda, Eiichi, Ishibashi, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689213/
https://www.ncbi.nlm.nih.gov/pubmed/34977620
http://dx.doi.org/10.1016/j.asmr.2021.07.024
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author Kimura, Yuka
Yamamoto, Yuji
Sasaki, Shizuka
Sasaki, Eiji
Sasaki, Tomoyuki
Tsuda, Eiichi
Ishibashi, Yasuyuki
author_facet Kimura, Yuka
Yamamoto, Yuji
Sasaki, Shizuka
Sasaki, Eiji
Sasaki, Tomoyuki
Tsuda, Eiichi
Ishibashi, Yasuyuki
author_sort Kimura, Yuka
collection PubMed
description PURPOSE: To investigate the clinical outcomes following meniscus allograft transplantation (MAT) to replace removed discoid lateral meniscus using intact lateral meniscus obtained from patients undergoing total knee arthroplasty for medial compartment osteoarthritis. METHODS: Pediatric patients who underwent MAT secondary to partial or total meniscectomy due to discoid lateral meniscus between August 2010 and November 2018 were identified. Lateral menisci with bone blocks were transplanted arthroscopically. The demographic data, range of motion, meniscal allograft failure, which was defined as removal of an implanted meniscus, and complications were recorded. The Lysholm score and the Kellgren-Lawrence (KL) grade on radiographs were evaluated preoperatively and at final follow-up. The Knee injury and Osteoarthritis Outcome Score was evaluated in the final follow-up. RESULTS: Eight patients who were symptomatic after discoid lateral meniscectomy were included. Donated allografts were harvested from adult patients aged between 64 and 78 years (mean 70.5 years). The mean age at previous meniscectomy and MAT were 10.5 and 18.1 years, respectively. All patients were followed up for a mean time of 5.2 years, and there were no cases of meniscus failure and complication. The Lysholm score significantly improved from preoperative to the final follow-up. Preoperatively, 6 and 2 knees were of KL grades II and III, respectively. At final follow-up, no increased KL grade was observed in 5 patients; however, an increase by 1 grade was observed in 2 patients and an increase by 2 grades was observed in 1 patient. The Knee injury and Osteoarthritis Outcome Scores at the final follow-up were 87.2 for pain, 87.9 for symptoms, 95.4 for activities of daily living, 79.4 for sports, and 65.6 for quality of life. CONCLUSIONS: Older lateral meniscus allografts obtained from knees of adult patients undergoing total knee arthroplasty and transplanted into younger patients with defects from discoid lateral meniscectomy resulted in improved Lysholm scores but no improvement in Tegner scores or knee motion. KL grades were unchanged in 5 of the 8 patients at the final follow-up. LEVEL OF EVIDENCE: IV, therapeutic case series.
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spelling pubmed-86892132021-12-30 Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy Kimura, Yuka Yamamoto, Yuji Sasaki, Shizuka Sasaki, Eiji Sasaki, Tomoyuki Tsuda, Eiichi Ishibashi, Yasuyuki Arthrosc Sports Med Rehabil Original Article PURPOSE: To investigate the clinical outcomes following meniscus allograft transplantation (MAT) to replace removed discoid lateral meniscus using intact lateral meniscus obtained from patients undergoing total knee arthroplasty for medial compartment osteoarthritis. METHODS: Pediatric patients who underwent MAT secondary to partial or total meniscectomy due to discoid lateral meniscus between August 2010 and November 2018 were identified. Lateral menisci with bone blocks were transplanted arthroscopically. The demographic data, range of motion, meniscal allograft failure, which was defined as removal of an implanted meniscus, and complications were recorded. The Lysholm score and the Kellgren-Lawrence (KL) grade on radiographs were evaluated preoperatively and at final follow-up. The Knee injury and Osteoarthritis Outcome Score was evaluated in the final follow-up. RESULTS: Eight patients who were symptomatic after discoid lateral meniscectomy were included. Donated allografts were harvested from adult patients aged between 64 and 78 years (mean 70.5 years). The mean age at previous meniscectomy and MAT were 10.5 and 18.1 years, respectively. All patients were followed up for a mean time of 5.2 years, and there were no cases of meniscus failure and complication. The Lysholm score significantly improved from preoperative to the final follow-up. Preoperatively, 6 and 2 knees were of KL grades II and III, respectively. At final follow-up, no increased KL grade was observed in 5 patients; however, an increase by 1 grade was observed in 2 patients and an increase by 2 grades was observed in 1 patient. The Knee injury and Osteoarthritis Outcome Scores at the final follow-up were 87.2 for pain, 87.9 for symptoms, 95.4 for activities of daily living, 79.4 for sports, and 65.6 for quality of life. CONCLUSIONS: Older lateral meniscus allografts obtained from knees of adult patients undergoing total knee arthroplasty and transplanted into younger patients with defects from discoid lateral meniscectomy resulted in improved Lysholm scores but no improvement in Tegner scores or knee motion. KL grades were unchanged in 5 of the 8 patients at the final follow-up. LEVEL OF EVIDENCE: IV, therapeutic case series. Elsevier 2021-09-10 /pmc/articles/PMC8689213/ /pubmed/34977620 http://dx.doi.org/10.1016/j.asmr.2021.07.024 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Kimura, Yuka
Yamamoto, Yuji
Sasaki, Shizuka
Sasaki, Eiji
Sasaki, Tomoyuki
Tsuda, Eiichi
Ishibashi, Yasuyuki
Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy
title Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy
title_full Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy
title_fullStr Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy
title_full_unstemmed Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy
title_short Meniscus Allograft Transplantation Obtained From Adult Patients Undergoing Total Knee Arthroplasty May be Used for Younger Patients After Lateral Discoid Meniscus Meniscectomy
title_sort meniscus allograft transplantation obtained from adult patients undergoing total knee arthroplasty may be used for younger patients after lateral discoid meniscus meniscectomy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689213/
https://www.ncbi.nlm.nih.gov/pubmed/34977620
http://dx.doi.org/10.1016/j.asmr.2021.07.024
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