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Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke
Ischemic stroke is the second leading cause of death worldwide. Following an ischemic event, neuronal death is triggered by uncontrolled glutamate release leading to overactivation of glutamate sensitive N-methyl-d-aspartate receptor (NMDAR). For gating, NMDARs require not only the binding of glutam...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689229/ https://www.ncbi.nlm.nih.gov/pubmed/34977503 http://dx.doi.org/10.1016/j.isci.2021.103539 |